DTCC- Depository Trust & Clearing Corporation Daniel Guidotti 14 years ago DTCC- Depository Trust & Clearing CorporationWas set up in 1999 as a holding company with 5 clearing corporations plus 1 depository. It is the biggest financial services corporation worldwide engaging in transactions that occur post trade.Recommended for you:DTC- Depository Trust Company Mortgage-Backed Securities Clearing Corporation International Depository Receipt (IDR) MBS Depository